GFRA1 抗体
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北京 101111
Quick Overview for GFRA1 抗体 (ABIN5542200)
抗原
See all GFRA1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects Human GFRa-1 and doesn't cross-react with hGFRa-2, hGFRa-3, hGFRa-4. Other species not tested.
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纯化方法
- Affinity Chromatography
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免疫原
- Recombinant His-tagged human GFRa-1 protein produced using CHO-based. For production of hGFRa-1, glycosylphosphatidyl-inositol GPI-anchor was removed and protein was secreted to the cell culture supernatant. Protein was purified by Ni-affinity chromatography following gel-filtration from cell culture supernatant.
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亚型
- IgY
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应用备注
- ELISA: 1/80000-1/160000. Western blot: 1/5000-1/10000. Immunofluorescence: 1/1000-1/2000.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Concentrated Ammonium Sulphate in PBS pH 7.4
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储存条件
- 4 °C
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储存方法
- Upon receipt, store at 2-8°C. As product is (NH4) 2 SO 4 precipitate, mix well by pipetting or vortexing prior use. Shelf life: One year from despatch.
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- GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))
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别名
- gfra1,gdnfr-alpha
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背景
- Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The GFRa-1 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor (www.ncbi.nlm.nih.gov/gene/2674).
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UniProt
- P56159
抗原
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