PSG1 抗体
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北京 101111
Quick Overview for PSG1 抗体 (ABIN5542089)
抗原
See all PSG1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts to Pregnancy-specifc Glycoproteins (PSG1-11). Species: Human.
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纯化方法
- Affinity chromatography on Protein G
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免疫原
- Immunisation with extracted protein of human PSG
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亚型
- IgG1
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应用备注
- Flow cytometry: 1.2 μg/10e6 cells.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Phosphate buffered saline, pH 7.2
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- PSG1 (Pregnancy Specific beta-1-Glycoprotein 1 (PSG1))
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别名
- cd66f,psg1
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背景
- The human pregnancy-specific glycoprotein family (PSG) is a group of closely related secreted glycoproteins which are highly expressed in placental syncytiotrophoblast cells of fetal origin (1). PSG are commonly expressed in tumors of trophoblast origin (hydatidiform mole, choriocarci-noma). They represent the most abundant fetal protein in the maternal blood at term. Together with the carcinoembryonic antigen (CEA)-related cell adhesion molecule (CEACAM) genes, the human PSG genes form the CEACAM gene family (2). PSG stimulate secretion of TH2-type cytokines from monocytes. CD9 was shown to represent the monocyte receptor for murine PSG17 (3). PSG are thought to modulate the maternal immune system during pregnancy thus protecting the semiallotypic fetus from rejection (4).
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UniProt
- P11464
抗原
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