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PARK7/DJ1 抗体 (AA 1-189)

This 小鼠 单克隆 anti-PARK7/DJ1 antibody (Clone AT1E12) specifically detects PARK7/DJ1 in WB, IF, ICC, FACS 和 EIA. The antibody is reactive with 人 samples.
产品编号 ABIN5542009
发货至: 中国
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Quick Overview for PARK7/DJ1 抗体 (AA 1-189) (ABIN5542009)

抗原

See all PARK7/DJ1 (PARK7) 抗体
PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This PARK7/DJ1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

克隆位点

AT1E12
  • 抗原表位

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    AA 1-189

    纯化方法

    Protein-A affinity chromatography

    免疫原

    Recombinant human Park7/DJ-1 (1-189aa) purified from E. coli

    亚型

    IgG2b
  • 应用备注

    ELISA. Flow Cytometry. Immunocytochemistry/Immunofluorescence. Western blot / Immunoblot. The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))

    别名

    dj-1,park7

    背景

    Parkinson disease (autosomal recessive, early onset) 7, also known as PARK7/DJ-1, has been shown to interact with EFCAB6 and protein inhibitor of activated STAT2. Defects in PARK7 are the cause of autosomal recessive early-onset Parkinson's disease 7. This protein belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death.

    UniProt

    Q99497

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Proton Transport
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