PARK7/DJ1 抗体
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北京 101111
Quick Overview for PARK7/DJ1 抗体 (ABIN5542008)
抗原
See all PARK7/DJ1 (PARK7) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody is specific for the ~21k park7 protein.
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纯化方法
- Affinity Chromatography
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免疫原
- Full length recombinant human park7 expressed in and purified from E. coli.
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亚型
- IgG1
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应用备注
- Western blotting: 1/2000. Immunofluorescence: 1/500.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS Preservatives: 10 mM Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the antibody undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))
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别名
- dj-1,park7
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背景
- Park7, also known as DJ-1, is a member of the peptidase C56 family of proteins and is thought to function as a molecular chaperone. Mutations in park7 have been associated with autosomal recessive, early onset Parkinson's disease (Bonifati et al., 2003). Recently, park7 has been shown to inhibit microtubule associated protein 1B aggregation thus leading to neuronal apoptosis (Wang et al., 2011).
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UniProt
- O88767
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Proton Transport
抗原
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