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CD46 抗体 (AA 35-313)

This anti-CD46 antibody is a 小鼠 单克隆 antibody detecting CD46 in WB 和 EIA. Suitable for 人.
产品编号 ABIN5541991
发货至: 中国

Quick Overview for CD46 抗体 (AA 35-313) (ABIN5541991)

抗原

See all CD46 抗体
CD46

适用

  • 130
  • 37
  • 23
  • 11
  • 10
  • 3

宿主

  • 91
  • 62
  • 2
  • 1
小鼠

克隆类型

  • 78
  • 78
单克隆

标记

  • 63
  • 17
  • 14
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  • 4
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  • 3
  • 2
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CD46 antibody is un-conjugated

应用范围

  • 92
  • 87
  • 42
  • 41
  • 39
  • 24
  • 22
  • 14
  • 14
  • 9
  • 8
  • 5
  • 4
  • 2
  • 2
  • 1
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  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)

克隆位点

AT2G9
  • 抗原表位

    • 16
    • 10
    • 7
    • 6
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    • 2
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 35-313

    纯化方法

    Protein-A affinity chromatography

    免疫原

    Recombinant human CD46 (35-313aa) purified from E. coli.

    亚型

    IgG2a
  • 应用备注

    The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    CD46

    别名

    cd46,mcp

    背景

    Membrane Cofactor Protein (CD46) is a type 1 membrane protein that plays an important inhibitory role in the complement system. CD46 regulates the complement cascade by inhibiting C3b and C4b deposited on self tissue. This protein is a cofactor that binds to C3b and C4b, allowing their degradation by a plasma serine protease called factor I. This function resides in the complement control protein repeats (CCPs), with CCP1-4 essential for regulation. CD46 is implicated in the development and/or progression of selected cancer types.

    UniProt

    P15529

    途径

    Regulation of Actin Filament Polymerization
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