CD46 抗体
Quick Overview for CD46 抗体 (ABIN5541990)
抗原
See all CD46 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The monoclonal antibody MM.1 recognizes CD46, also known as membrane cofactor protein.
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纯化方法
- Purified
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亚型
- IgG1
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anti-CD46 (CD46) (AA 40-320) antibody
CD46 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD46 (CD46) (AA 35-179) antibodyCD46 适用: 人 WB, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 5A8C11 unconjugated
anti-CD46 (CD46) (AA 35-179) antibodyCD46 适用: 人 FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 1A5A5 unconjugated
anti-CD46 (CD46) (AA 317-343) antibodyCD46 适用: 人 WB, FACS, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-CD46 (CD46) (AA 251-355) antibodyCD46 适用: 人, 小鼠 WB, FACS, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-CD46 (CD46) antibodyCD46 适用: 人, Cow WB, FACS, IP 宿主: 小鼠 Monoclonal MEM-258 unconjugated
anti-CD46 (CD46) antibodyCD46 适用: 人, Cow WB, FACS, IP 宿主: 小鼠 Monoclonal MEM-258 unconjugated
anti-CD46 (CD46) antibodyCD46 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 7D12 unconjugated Recombinant Antibody
anti-CD46 (CD46) antibody (Biotin)CD46 适用: 人, Cow WB, FACS, IP 宿主: 小鼠 Monoclonal MEM-258 Biotin
anti-CD46 (CD46) antibody (FITC)CD46 适用: 人, Cow FACS 宿主: 小鼠 Monoclonal MEM-258 FITC
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应用备注
- Western blot: Rat testis lysate, non-reducing conditions, band size 38 kDa (Ref.1,4). Immuno Assays (Ref.1). Immunofluorescence (Ref.2-4). Immunohistochemistry on Frozen Sections (Ref.1-3). The typical starting working dilution is 1/50.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Buffer System: PBS Stabilizers: 0.1 % BSA
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储存条件
- 4 °C
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储存方法
- Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
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有效期
- 12 months
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- CD46
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别名
- cd46,mcp
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背景
- An immunohistological survey of rat tissues revealed that CD46 is expressed only in the testis and epididymis of adult rats more specifically, only by spermatozoa and late spermatozoal precursors. In contrast, in humans, CD46 is expressed on every cell and tissue, with the exception of erythrocytes. CD46 serves to down-regulate the activation of complement on host tissue. It functions as a cofactor by binding to C3b and C4b. Binding is permitted by factor I, a serine protease of plasma, to degrade C3b and C4b and serves to protect the host cell against autologous attack. In human, it also serves as a receptor for measles virus. Two isoforms of CD46 predominate and arise by alternative splicing of a single CD46 gene. The isoforms differ in the length. CD46 cDNA encodes a signal sequence followed by four complement control protein domains (also called short consensus repeats (SCR)).
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UniProt
- Q9Z0M4
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途径
- Regulation of Actin Filament Polymerization
抗原
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