CD46 抗体
Quick Overview for CD46 抗体 (ABIN5541989)
抗原
See all CD46 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The monoclonal antibody MM10 recognizes membrane cofactor protein (MCP), also known as CD46.
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纯化方法
- Purified
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免疫原
- Mouse CD46-human Fc fusion protein.
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亚型
- IgG2a
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anti-CD46 (CD46) (AA 40-320) antibody
CD46 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD46 (CD46) (AA 35-179) antibodyCD46 适用: 人 WB, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 5A8C11 unconjugated
anti-CD46 (CD46) (AA 35-179) antibodyCD46 适用: 人 FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 1A5A5 unconjugated
anti-CD46 (CD46) (AA 317-343) antibodyCD46 适用: 人 WB, FACS, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-CD46 (CD46) (AA 251-355) antibodyCD46 适用: 人, 小鼠 WB, FACS, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-CD46 (CD46) antibodyCD46 适用: 人, Cow WB, FACS, IP 宿主: 小鼠 Monoclonal MEM-258 unconjugated
anti-CD46 (CD46) antibodyCD46 适用: 人, Cow WB, FACS, IP 宿主: 小鼠 Monoclonal MEM-258 unconjugated
anti-CD46 (CD46) antibodyCD46 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 7D12 unconjugated Recombinant Antibody
anti-CD46 (CD46) antibody (Biotin)CD46 适用: 人, Cow WB, FACS, IP 宿主: 小鼠 Monoclonal MEM-258 Biotin
anti-CD46 (CD46) antibody (FITC)CD46 适用: 人, Cow FACS 宿主: 小鼠 Monoclonal MEM-258 FITC
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应用备注
- Immuno Assays (Detector) Positive Control: Rat CD46 or Mouse CD46 variant as coating on a micro titer plate. Western blot (Researcher data). Flow Cytometry (Researcher data) Immunefluorescence Immuno histochemistry on Frozen Sections The typical starting working dilution is 1/50.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Buffer System: PBS Preservatives: 0.02 % Sodium Azide Stabilizers: 0.1 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
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有效期
- 12 months
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- CD46
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别名
- cd46,mcp
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背景
- MCP is a type I membrane glycoprotein that consists of four isoforms i.e. two C-isoforms (51-58 kDa) and two BC isoforms (59-68 kDa) which arise by alternative splicing of a single CD46 gene. Membrane cofactor protein is expressed on every cell and tissue, with the exception of erythrocytes. Membrane cofactor protein serves to down-regulate the activation of complement on host tissue. MCP is a cofactor for factor 1-mediated cleavage of C3b and C4b and this way serves to protect the host cell against autologous attack. MCP is a receptor for several pathogens including measles virus, group A Streptococcus pyogenes and pathogenic Neisseria.
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UniProt
- O88174
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途径
- Regulation of Actin Filament Polymerization
抗原
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