我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

K-RAS 抗体 (AA 1-186)

Name: K-RAS 抗体 (AA 1-186)
SKU: ABIN5541964
Availability: OutOfStock

This anti-K-RAS antibody is a 小鼠单克隆 antibody detecting K-RAS in WB, IF, FACS, ICC 和 EIA. Suitable for 人.

产品编号 ABIN5541964

发货至: 中国

Datasheet as PDF

Quick Overview for K-RAS 抗体 (AA 1-186) (ABIN5541964)

抗原

See all K-RAS (KRAS) 抗体

K-RAS (KRAS) (GTPase Kras (KRAS))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This K-RAS antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Enzyme Immunoassay (EIA)

克隆位点

AT2F8

Discover our top product KRAS Primary Antibody

抗原表位
16

10

8

7

6

6

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-186

纯化方法

Protein-A affinity chromatography

免疫原

Recombinant human KRAS (1-186aa) purified from E. coli.
anti-GTPase Kras (KRAS) (AA 1-188) antibody
KRAS 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3B10-2F2 unconjugated

anti-GTPase Kras (KRAS) (AA 16-125) antibody
KRAS 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4F3 unconjugated

anti-GTPase Kras (KRAS) (AA 146-174) antibody
KRAS 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-GTPase Kras (KRAS) (AA 25-130) antibody
KRAS 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-GTPase Kras (KRAS) (AA 2-168) antibody
KRAS 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-GTPase Kras (KRAS) (N-Term) antibody
KRAS 适用: 人, 大鼠, 小鼠, 犬, 斑马鱼, 兔, 马, 豚鼠, Cow, Drosophila melanogaster, Pig, Bat, 小鸡, 非洲爪蟾, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-GTPase Kras (KRAS) (pSer89) antibody
KRAS 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-GTPase Kras (KRAS) (N-Term) antibody
KRAS 适用: 人, 大鼠, 小鼠, 犬, 斑马鱼, 兔, 马, 豚鼠, Cow, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated

anti-GTPase Kras (KRAS) (AA 1-189) antibody
KRAS 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-GTPase Kras (KRAS) antibody
KRAS 适用: 人 WB 宿主: 小鼠 Monoclonal 2C1 unconjugated

应用备注

The antibody has been tested by ELISA, Western blot analysis, ICC/IF and Flow cytometry to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

限制

仅限研究用
状态

Liquid

缓冲液

Liquid. In Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % Glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

有效期

12 months
抗原

K-RAS (KRAS) (GTPase Kras (KRAS))

别名

kras

物质类

Viral Protein

背景

KRAS acts as a molecular on/off switch. Once it is turned on, it recruits and activates proteins necessary for the propagation of growth factor and other receptors' sigl such as c-Raf and PI 3-kise. KRAS binds to GTP in the active state and possesses an intrinsic enzymatic activity which cleaves the termil phosphate of the nucleotide converting it to GDP. Upon conversion of GTP to GDP, KRAS is turned off. The rate of conversion is usually slow but can be sped up dramatically by an accessory protein of the GTPase-activating protein (GAP) class, for example RasGAP. In turn KRAS can bind to proteins of the Guanine Nucleotide Exchange Factor (GEF) class, for example SOS1, which forces the release of bound nucleotide (GDP). Subsequently, KRAS binds GTP present in the cytosol and the GEF is released from ras-GTP.

UniProt

P01116