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CD4 抗体 (PE)

There are 2+ publications for this product available. The 小鼠 单克隆 anti-CD4 antibody is suitable to detect CD4 in samples from 马. It has been validated for FACS.
产品编号 ABIN5541942
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD4 抗体 (PE) (ABIN5541942)

抗原

See all CD4 抗体
CD4

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD4 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

CVS4
  • 特异性

    This anitbody CVS4 recognizes Equine CD4, a 58 kDa cell surface glycoprotein that is primarily expressed on a subpopulation of equine T lymphocytes and considered to be the equine homologue of human CD4. A study undertaken using Mouse anti Horse CD4, clone CVS4 to identify CD4 on several wild african equid species indicates that the CVS4 clone recognizes Somali wild ass (Equus asinus) but not Grévy's Zebra (E. grevyi) or Hartmann's Mountain Zebra (E. zebra).

    纯化方法

    Affinity Chromatography on Protein G

    免疫原

    Equine thymocytes. Spleen cells from immunised mice were fused with cells of the X63-Ag 8.653 mouse myeloma cell line.

    亚型

    IgG1
  • 应用备注

    Flow Cytometry : Use 10 μL of neat antibody to label 10 6 cells in 100 μL.

    限制

    仅限研究用
  • 储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Prior to and following reconstitution store the antibody at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Shelf life: one year from despatch.

    有效期

    12 months
  • De Schauwer, Piepers, Van de Walle, Demeyere, Hoogewijs, Govaere, Braeckmans, Van Soom, Meyer: "In search for cross-reactivity to immunophenotype equine mesenchymal stromal cells by multicolor flow cytometry." in: Cytometry. Part A : the journal of the International Society for Analytical Cytology, Vol. 81, Issue 4, pp. 312-23, (2012) (PubMed).

    Go, Zhang, Timoney, Cook, Horohov, Balasuriya: "Complex interactions between the major and minor envelope proteins of equine arteritis virus determine its tropism for equine CD3+ T lymphocytes and CD14+ monocytes." in: Journal of virology, Vol. 84, Issue 10, pp. 4898-911, (2010) (PubMed).

  • 抗原

    CD4

    别名

    cd4

    背景

    CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes (helper/inducer T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.

    UniProt

    F6Y6X8

    途径

    TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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