CD4 抗体
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北京 101111
Quick Overview for CD4 抗体 (ABIN5541941)
抗原
See all CD4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This anitbody reacts with T-helper cells, it recognises a 58 kDa cell surface glycoprotein that is primarily expressed on a subpopulation of equine T lymphocytes and considered to be the equine homologue of human CD4. Species: Equine (Horse).
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纯化方法
- Affinity chromatography on Protein G from tissue culture supernatant
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免疫原
- Equine thymocytes
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亚型
- IgG1
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应用备注
- Flow cytometry : 1/25-1/200, use 10 μL of this working dilution to label 10e6 cells in 100 μL. Immunohistochemistry on Frozen sections. Immunoprecipitation.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Containing 0.09 % Sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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: "Complex interactions between the major and minor envelope proteins of equine arteritis virus determine its tropism for equine CD3+ T lymphocytes and CD14+ monocytes." in: Journal of virology, Vol. 84, Issue 10, pp. 4898-911, (2010) (PubMed).
: "A point mutation in a herpesvirus polymerase determines neuropathogenicity." in: PLoS pathogens, Vol. 3, Issue 11, pp. e160, (2008) (PubMed).
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- CD4
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别名
- cd4
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背景
- CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes (helper/inducer T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.
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UniProt
- F6Y6X8
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途径
- TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
抗原
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