GZMK 抗体
Our Local Distributor
北京 101111
Quick Overview for GZMK 抗体 (ABIN5541918)
抗原
See all GZMK 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- This antibody reacts to Granzyme K (GZMK). Species: Human.
-
纯化方法
- Affinity Chromatography on Protein G
-
免疫原
- Genetic immunisation with cDNA encoding human Granzyme K
-
亚型
- IgG1
-
-
-
-
应用备注
- Flow cytometry: 1.2 μg/10 6 cells. ELISA: 1/200-1/400. ELISA (capture): Clone GM-6C3 as detection antibody. Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Phosphate buffered saline, pH 7.2
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
-
有效期
- 12 months
-
-
- GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))
-
别名
- granzyme k (gzmk)
-
背景
- Granzyme K (GrK) belongs to a family of trypsin-like serine proteases localised in the cytotoxic granules of activated T cells and NK cells. It encodes a 28 kDa serine protease whose gene is located on chromosome 5q11-12 close to the granzyme A-encoding gene. Like granzyme A, it has a trypsin-like specifity cleaving at the basic residues arginine and lysine. Granzyme K triggers rapid cell death independently of caspase activation with single-stranded DNA nicks and is primarily expressed in thymus, lung, spleen and peripheral blood leukocytes.
-
UniProt
- P49863
抗原
-