GZMK 抗体
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北京 101111
Quick Overview for GZMK 抗体 (ABIN5541917)
抗原
See all GZMK 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognizes Granzyme K (GZMK). Species: Human.
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纯化方法
- Affinity Chromatography on Protein G
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免疫原
- GM24C3 was generated by genetic immunisation of BALB/c mice with an immunisation vector containing the Granzyme K cDNA
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亚型
- IgG2b
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anti-Granzyme K (Granzyme 3, Tryptase II) (GZMK) (AA 27-264) antibody
GZMK 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Granzyme K (Granzyme 3, Tryptase II) (GZMK) (Internal Region) antibodyGZMK 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Granzyme K (Granzyme 3, Tryptase II) (GZMK) antibodyGZMK 适用: 人 ELISA, FACS, cELISA 宿主: 小鼠 Monoclonal GM-24C3 unconjugated
anti-Granzyme K (Granzyme 3, Tryptase II) (GZMK) (AA 44-227) antibodyGZMK 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Granzyme K (Granzyme 3, Tryptase II) (GZMK) (AA 61-110) antibodyGZMK 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Granzyme K (Granzyme 3, Tryptase II) (GZMK) antibodyGZMK 适用: 人 ELISA, FACS, cELISA 宿主: 小鼠 Monoclonal GM-26E7 unconjugated
anti-Granzyme K (Granzyme 3, Tryptase II) (GZMK) (Internal Region) antibodyGZMK 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Granzyme K (Granzyme 3, Tryptase II) (GZMK) (AA 87-121) antibodyGZMK 适用: 人 WB 宿主: 兔 Polyclonal RB52998 unconjugated
anti-Granzyme K (Granzyme 3, Tryptase II) (GZMK) (Internal Region) antibodyGZMK 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Granzyme K (Granzyme 3, Tryptase II) (GZMK) (AA 1-264) antibodyGZMK 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Flow Cytometry: 1.2 μg/10 6 cells. ELISA: 1/200-1/400. Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.2 without preservatives
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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: "Blockade of interleukin-13-mediated cell activation by a novel inhibitory antibody to human IL-13 receptor alpha1." in: Molecular immunology, Vol. 43, Issue 11, pp. 1799-807, (2006) (PubMed).
: "Differential expression of human granzymes A, B, and K in natural killer cells and during CD8+ T cell differentiation in peripheral blood." in: European journal of immunology, Vol. 35, Issue 9, pp. 2608-16, (2005) (PubMed).
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: "Blockade of interleukin-13-mediated cell activation by a novel inhibitory antibody to human IL-13 receptor alpha1." in: Molecular immunology, Vol. 43, Issue 11, pp. 1799-807, (2006) (PubMed).
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- GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))
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别名
- granzyme k (gzmk)
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背景
- Granzyme K (GrK) belongs to a family of trypsin-like serine proteases localised in the cytotoxic granules of activated T cells and NK cells. It encodes a 28 kDa serine protease whose gene is located on chromosome 5q11-12 close to the granzyme A-encoding gene. Like granzyme A, it has a trypsin-like specifity cleaving at the basic residues arginine and lysine. Granzyme K triggers rapid cell death independently of caspase activation with single-stranded DNA nicks and is primarily expressed in thymus, lung, spleen and peripheral blood leukocytes.
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UniProt
- P49863
抗原
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