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LRRC32 抗体

LRRC32 适用: 人 WB, FACS, IP, EIA 宿主: 小鼠 Monoclonal GARP5 unconjugated
产品编号 ABIN5541855
发货至: 中国
  • 抗原 See all LRRC32 抗体
    LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
    适用
    • 23
    • 9
    • 8
    • 1
    宿主
    • 21
    • 9
    • 1
    • 1
    小鼠
    克隆类型
    • 22
    • 10
    单克隆
    标记
    • 18
    • 6
    • 3
    • 2
    • 2
    • 1
    This LRRC32 antibody is un-conjugated
    应用范围
    • 15
    • 14
    • 14
    • 7
    • 3
    • 2
    • 2
    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
    特异性
    This antibody recognizes GARP / LRRC32, an approximately 80 kDa glycoprotein expressed e.g. on the surface of megakaryocytes, platelets and activated Treg cells.
    纯化方法
    Protein-A affinity chromatography
    免疫原
    Purified human sGARP protein
    克隆位点
    GARP5
    亚型
    IgG1
    Top Product
    Discover our top product LRRC32 Primary Antibody
  • 应用备注
    Flow cytometry. Immunoprecipitation. Western blot. ELISA.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Phosphate buffered saline (PBS) Preservatives: 15 mM sodium azide, approx. pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
    别名
    lrrc32,garp (LRRC32 产品)
    背景
    GARP (glycoprotein A repetitions predominant protein), also known as Garpin or LRRC32 (leucin-rich repeat containing protein 32) is an approximately 80 kDa transmembrane glycoprotein detected on the surface of megakaryocytes, platelets, and activated Treg cells. It binds to the latency-associated peptide (LAP) domain of pro-TGF beta and regulates its storage and activation. The expression of GARP on Treg cells seems to be necessary for their suppressive functions.
    UniProt
    Q14392
    途径
    Activated T Cell Proliferation
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