TBX2 抗体 (AA 554-702)
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Quick Overview for TBX2 抗体 (AA 554-702) (ABIN5541456)
抗原
See all TBX2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 554-702
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纯化方法
- Purified
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免疫原
- Derived by fusion of SP2/0 mouse myeloma cells with spleen cells from a BALB/c mouse immunized with a GST fusion protein corresponding to residues 554-702 of Human TBX2.
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亚型
- IgG1
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anti-T-Box 2 (TBX2) (AA 603-702) antibody
TBX2 适用: 人 ELISA, WB, IF, RNAi 宿主: 小鼠 Monoclonal 7G5 unconjugated
anti-T-Box 2 (TBX2) (C-Term) antibodyTBX2 适用: 人, 小鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-T-Box 2 (TBX2) (AA 401-500) antibodyTBX2 适用: 人, 小鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-T-Box 2 (TBX2) (AA 299-573) antibodyTBX2 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-T-Box 2 (TBX2) (Internal Region) antibodyTBX2 适用: 人, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-T-Box 2 (TBX2) (AA 603-702) antibodyTBX2 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 3B2 unconjugated
anti-T-Box 2 (TBX2) (AA 1-702) antibodyTBX2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-T-Box 2 (TBX2) (AA 287-336) antibodyTBX2 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-T-Box 2 (TBX2) (AA 72-121) antibodyTBX2 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, Cow, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot. Immunoprecipitation. Immunohistochemistry on Paraffin Sections.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Buffer System: PBS Preservatives: 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- TBX2 (T-Box 2 (TBX2))
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别名
- tbx2
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背景
- T-box transcription factor TBX2 is a protein that in humans is encoded by the TBX2 gene and with subcellulair location in the nucleus. This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene. In melanocytic cell types, expression of the T-box 2 gene is regulated by the Microphthalmia-associated transcription factor The oncogene TBX2 is a cooperating factor in transformation of pocket protein deficient MEFs. TBX2 downregulates the p53/p21CIP1 pathway both in wild-type and pocket protein deficient MEFs. Tissue specificity: expressed primarily in adult in kidney, lung, and placenta. Weak expression in heart and ovary.
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UniProt
- Q13207
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途径
- p53 Pathway
抗原
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