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MAPT 抗体 (pSer202)

The 兔 多克隆 anti-MAPT antibody is suitable to detect MAPT in samples from 人, 大鼠 和 小鼠. It has been validated for WB.
产品编号 ABIN5541354
发货至: 中国
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北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MAPT 抗体 (pSer202) (ABIN5541354)

抗原

See all MAPT 抗体
MAPT (Microtubule-Associated Protein tau (MAPT))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This MAPT antibody is un-conjugated

应用范围

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Western Blotting (WB)
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    pSer202

    特异性

    The antibody detects endogenous levels of Tau only when phosphorylated at serine 202.

    纯化方法

    Affinity chromatography using epitope-specific peptide

    免疫原

    Peptide sequence around phosphorylation site of serine 202(P-G-S(p)-P-G) derived from Human Tau (KLH-conjugated)
  • 应用备注

    Western blot: 1:500~1:1000.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    MAPT (Microtubule-Associated Protein tau (MAPT))

    别名

    mapt,tau

    背景

    Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

    UniProt

    P10636

    途径

    MAPK Pathway, Microtubule Dynamics, M Phase, Regulation of Cell Size
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