MAPT 抗体
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北京 101111
Quick Overview for MAPT 抗体 (ABIN5541353)
抗原
See all MAPT 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Specific for the ~48, 65 & 75 kDa Tau isoforms.
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纯化方法
- Ig Fraction
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免疫原
- Recombinant full length Human Tau expressed in and purified from E. coli.
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亚型
- Ig Fraction
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应用备注
- Western blotting: 1/10,000. Immunohistochemistry. Immunofluorescence: 1/1000.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Preservatives: 10 mM Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the antibody undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- MAPT (Microtubule-Associated Protein tau (MAPT))
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别名
- mapt,tau
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背景
- Tau is a key microtubule-associated protein that plays an important role in the formation of microtubules in axons (Binder et al. 1985). Six tau isoforms have been identified as products of a single gene produced by alternative mRNA splicing (Goedert 1990). Tau mutations have been implicated in many neurodegenerative disorders such as Alzheimer's disease (AD), Pick's disease and progressive supranuclear palsy.
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UniProt
- P10636
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途径
- MAPK Pathway, Microtubule Dynamics, M Phase, Regulation of Cell Size
抗原
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