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CD55 抗体

CD55 适用: Pig WB, FACS, EIA 宿主: 小鼠 Monoclonal PD2 unconjugated
产品编号 ABIN5541173
发货至: 中国
  • 抗原 See all CD55 抗体
    CD55 (Complement Decay-Accelerating Factor (CD55))
    适用
    • 109
    • 35
    • 7
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Pig
    宿主
    • 69
    • 65
    • 6
    • 6
    • 3
    • 1
    • 1
    小鼠
    克隆类型
    • 80
    • 69
    • 2
    单克隆
    标记
    • 71
    • 17
    • 16
    • 11
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD55 antibody is un-conjugated
    应用范围
    • 97
    • 75
    • 47
    • 39
    • 33
    • 24
    • 16
    • 15
    • 14
    • 13
    • 9
    • 3
    • 3
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    • 1
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    Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
    特异性
    The monoclonal antibody PD2 recognizes Pig complement decay accelerating factor (DAF), also designated as CD55.
    纯化方法
    Purified
    免疫原
    Pig DAF-Ig fusion protein.
    克隆位点
    PD2
    亚型
    IgG1
    Top Product
    Discover our top product CD55 Primary Antibody
  • 应用备注
    Immuno Assays. Flow Cytometry (Ref.2). Western blot. Positive Control: Porcine platelet lysate. Typical starting working dilution: 1/50.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Buffer System: PBS Stabilizers: 0.1 % BSA
    储存条件
    4 °C
    储存方法
    Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    CD55 (Complement Decay-Accelerating Factor (CD55))
    别名
    cd55,daf (CD55 产品)
    别名
    CR antibody, CROM antibody, DAF antibody, TC antibody, Daf antibody, Daf-GPI antibody, Daf1 antibody, GPI-DAF antibody, CD55 molecule (Cromer blood group) antibody, CD55 molecule, decay accelerating factor for complement antibody, CD55 antibody, Cd55 antibody
    背景
    Cells express on their surface several proteins which protect against complement attack, namely C receptor I (CR1), decay accelerating factor (DAF), membrane cofactor protein (MCP) and CD59. CR1, DAF and MCP regulate the activation pathways of complement by either accelerating decay of the C3 and C5 convertase (CR1, DAF), or acting as cofactors for the serine protease factor I, which cleaves and irreversibly inactivates C3b (CR1, MCP). Pig DAF (CD55) is a 45-52 kDa transmembrane protein that binds C3b and C4b to inhibit formation and half-life of the C3 convertases. DAF is broadly distributed among cells in contact with serum, including both haematopoietic and nonhaematopoietic cells. Although DAF does not have an essential role in controlling hemolysis of erythrocytes, it has an important role in regulation of the deposition of C3 on nucleated cells. Together with other complement regulators DAF protects self cells from autologous complementmediated injury. DAF cooperates with CD46 in circumventing autologous C3 deposition, while CD59 inhibits the pathway at the critical end-point.
    UniProt
    P08174
    途径
    Complement System, Regulation of Leukocyte Mediated Immunity
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