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CD55 抗体

This 小鼠 单克隆 anti-CD55 antibody (Clone PD2) specifically detects CD55 in WB, FACS 和 EIA. The antibody is reactive with Pig samples.
产品编号 ABIN5541173
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD55 抗体 (ABIN5541173)

抗原

See all CD55 抗体
CD55 (Complement Decay-Accelerating Factor (CD55))

适用

  • 149
  • 32
  • 7
  • 4
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  • 2
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  • 1
Pig

宿主

  • 97
  • 77
  • 6
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  • 1
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小鼠

克隆类型

  • 125
  • 63
  • 2
单克隆

标记

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This CD55 antibody is un-conjugated

应用范围

  • 104
  • 93
  • 46
  • 41
  • 35
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Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

克隆位点

PD2
  • 特异性

    The monoclonal antibody PD2 recognizes Pig complement decay accelerating factor (DAF), also designated as CD55.

    纯化方法

    Purified

    免疫原

    Pig DAF-Ig fusion protein.

    亚型

    IgG1
  • 应用备注

    Immuno Assays. Flow Cytometry (Ref.2). Western blot. Positive Control: Porcine platelet lysate. Typical starting working dilution: 1/50.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer System: PBS Stabilizers: 0.1 % BSA

    储存条件

    4 °C

    储存方法

    Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    CD55 (Complement Decay-Accelerating Factor (CD55))

    别名

    cd55,daf

    背景

    Cells express on their surface several proteins which protect against complement attack, namely C receptor I (CR1), decay accelerating factor (DAF), membrane cofactor protein (MCP) and CD59. CR1, DAF and MCP regulate the activation pathways of complement by either accelerating decay of the C3 and C5 convertase (CR1, DAF), or acting as cofactors for the serine protease factor I, which cleaves and irreversibly inactivates C3b (CR1, MCP). Pig DAF (CD55) is a 45-52 kDa transmembrane protein that binds C3b and C4b to inhibit formation and half-life of the C3 convertases. DAF is broadly distributed among cells in contact with serum, including both haematopoietic and nonhaematopoietic cells. Although DAF does not have an essential role in controlling hemolysis of erythrocytes, it has an important role in regulation of the deposition of C3 on nucleated cells. Together with other complement regulators DAF protects self cells from autologous complementmediated injury. DAF cooperates with CD46 in circumventing autologous C3 deposition, while CD59 inhibits the pathway at the critical end-point.

    UniProt

    P08174

    途径

    Complement System, Regulation of Leukocyte Mediated Immunity
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