CD55 抗体
Quick Overview for CD55 抗体 (ABIN5541170)
抗原
See all CD55 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The monoclonal antibody 3D5 recognizes complement decay accelerating factor (DAF), also designated as CD55.
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纯化方法
- Protein G Chromatography
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免疫原
- NRK cells expressing transmembrane-anchored Mouse DAF
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亚型
- IgG2a
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anti-Complement Decay-Accelerating Factor (CD55) (AA 35-134) antibody
CD55 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1G3 unconjugated
anti-Complement Decay-Accelerating Factor (CD55) (AA 35-285) antibodyCD55 适用: 人 WB, ELISA, IHC (fro), ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Complement Decay-Accelerating Factor (CD55) (AA 40-300) antibodyCD55 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Complement Decay-Accelerating Factor (CD55) (AA 51-79) antibodyCD55 适用: 人 WB, FACS, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Complement Decay-Accelerating Factor (CD55) (AA 35-134) antibodyCD55 适用: 人 WB, IF, ELISA 宿主: 小鼠 Monoclonal 1D7 unconjugated
anti-Complement Decay-Accelerating Factor (CD55) (Center) antibodyCD55 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Decay-Accelerating Factor (CD55) (AA 254-372) antibodyCD55 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Decay-Accelerating Factor (CD55) (AA 35-126) antibodyCD55 适用: 人 IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Complement Decay-Accelerating Factor (CD55) antibodyCD55 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 1A5 unconjugated Recombinant Antibody
anti-Complement Decay-Accelerating Factor (CD55) antibodyCD55 适用: 人 FACS, IF 宿主: 小鼠 Monoclonal F4-29D9 unconjugated
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应用备注
- Flow Cytometry. Western blot. The typical starting working dilution is 1/50.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS Preservatives: 0.02 % Sodium Azide Stabilizers: 0.1 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
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有效期
- 12 months
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- CD55 (Complement Decay-Accelerating Factor (CD55))
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别名
- cd55,daf
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背景
- Cells express on their surface several proteins which protect against complement attack, namely C receptor I (CR1), decay accelerating factor (DAF), membrane cofactor protein (MCP) and CD59. CR1, DAF and MCP regulate the activation pathways of complement by either accelerating decay of the C3 and C5 convertase (CR1, DAF), or acting as cofactors for the serine protease factor I, which cleaves and irreversibly inactivates C3b (CR1, MCP). Mouse DAF (CD55) is a 60 kDa transmembrane protein that binds C3b and C4b to inhibit formation and half-life of the C3 convertases. DAF is broadly distributed among cells in contact with serum, including both haematopoietic and nonhaematopoietic cells. Although DAF does not have an essential role in controlling hemolysis of erythrocytes, it has an important role in regulation of the deposition of C3 on nucleated cells. Together with other complement regulators DAF protects self cells from autologous complementmediated injury. DAF cooperates with CD46 in circumventing autologous C3 deposition, while CD59 inhibits the pathway at the critical end-point.
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UniProt
- Q61475
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途径
- Complement System, Regulation of Leukocyte Mediated Immunity
抗原
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