CCRL2 抗体
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北京 101111
Quick Overview for CCRL2 抗体 (ABIN5541108)
抗原
See all CCRL2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody detects human CCRL2.
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纯化方法
- Protein G
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免疫原
- DNA vaccine
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亚型
- IgG2a
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anti-Chemokine (C-C Motif) Receptor-Like 2 (CCRL2) antibody
CCRL2 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor-Like 2 (CCRL2) (AA 1-43) antibodyCCRL2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor-Like 2 (CCRL2) (Internal Region) antibodyCCRL2 适用: 人, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor-Like 2 (CCRL2) (Cytoplasmic Domain) antibodyCCRL2 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor-Like 2 (CCRL2) (AA 1-24) antibodyCCRL2 适用: 小鼠 WB, ELISA, IHC, FACS, ICC, Func, IP 宿主: 兔 Chimeric BZ5B8 unconjugated Recombinant Antibody
anti-Chemokine (C-C Motif) Receptor-Like 2 (CCRL2) (AA 1-344) antibodyCCRL2 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor-Like 2 (CCRL2) (Internal Region) antibodyCCRL2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor-Like 2 (CCRL2) (AA 1-344) antibodyCCRL2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor-Like 2 (CCRL2) (AA 36-85) antibodyCCRL2 适用: 人, Cow, 豚鼠, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor-Like 2 (CCRL2) (AA 141-190) antibodyCCRL2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Immunohistochemistry on paraffin sections: 4-8 μg/mL (1/50-1/100). Positive control: Human placenta.
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限制
- 仅限研究用
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缓冲液
- Phosphate buffered saline pH 7.2 (PBS) Preservatives: 0.1 % Kathon Stabilizers: 5 mg/mL bovine serum albumin (BSA)
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储存条件
- 4 °C,-20 °C
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储存方法
- Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- CCRL2 (Chemokine (C-C Motif) Receptor-Like 2 (CCRL2))
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别名
- ccrl2,ccr11
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背景
- Lipopolysaccharide-inducible CC chemokine receptor (LCCR), or CCRL2 is a 344 amino acid protein that belongs to the G - protein coupled receptor 1 family, with a potential glycosylation site and one disulfide bond. CCRL2 is e xp ressed abundantly in immunal tissues such as spleen, fetal liver, lymph node and bone marrow, but also in lung and heart. CCRL2 is e xpressed in almost all hematopoietic cells including monocytes, macrophages, PMNs, T - cells (both CD4+ and CD8+), monocyte - de rived iDCs, NK cells, and CD34+ progenitor cells, and also on glial cells and mast cells at inflammatory sites. It has been reported to be up - regulated on synovial neutrophils of rheumatoid arthritis patients. Unlike other known G - protein coupled receptors, binding of an agonist such as CCL5 or CCL19 does not induce signal transduction through CCRL2. Rather, the ligand is absorbed after binding, and the receptor recycled, thus reducing the local ligand concentration. The leukocyte chemoattractant chemerin is a ligand for CCRL2 as well, but rather than being recycled, the complex seems to promote bridging to the chemerin receptor on nearby cells.
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UniProt
- O00421
抗原
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