This antobody recognizes CD157, an approximately 45 kDa GPI-anchored protein expressed mainly on monocytes, macrophages, granulocytes and bone marrow stromal cells.
纯化方法
Protein-A affinity chromatography (> 95% pure by SDS-PAGE)
Flow cytometry. Immunoprecipitation. Western blot: non-reducing conditions. Immunohistochemistry (frozen sections).
限制
仅限研究用
状态
Liquid
缓冲液
95 % pure by SDS-PAGE) Buffer System: Phosphate buffered saline (PBS) Preservatives: 15 mM sodium azide, approx. pH 7.4
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C
储存方法
Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
有效期
12 months
抗原
BST1
(Bone Marrow Stromal Cell Antigen 1 (BST1))
别名
cd157,bst1
背景
CD157 (cADPr hydrolase 2) is a GPI-anchored ectoenzyme possessing ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase activity. It uses NAD and cADP-ribose as substrates. CD157 is expressed on granulocytes, monocytes, macrophages, follicular dendritic cells, bone marrow stromal cells and human umbilical cord vein endothelial cells. In case of rheumatoid arthritis is expression is often higher and it is also differentially expressed in the myeloid leukemias. It may also have a signaling role.