Cytokeratin 5 抗体 (AA 1-590)
Quick Overview for Cytokeratin 5 抗体 (AA 1-590) (ABIN5540901)
抗原
See all Cytokeratin 5 (KRT5) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-590
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纯化方法
- Protein-A affinity chromatography
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免疫原
- Recombinant human KRT5 (1-590aa) purified from E. coli.
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亚型
- IgG2a
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anti-Keratin 5 (KRT5) (AA 316-590) antibody
KRT5 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 10C11E6 unconjugated
anti-Keratin 5 (KRT5) antibodyKRT5 适用: 人, 小鼠, 猴 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 2C2 unconjugated
anti-Keratin 5 (KRT5) (AA 335-473) antibodyKRT5 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Keratin 5 (KRT5) (AA 316-590) antibodyKRT5 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal KRT5-3594 unconjugated
anti-Keratin 5 (KRT5) (AA 1-273) antibodyKRT5 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4A7 unconjugated
anti-Keratin 5 (KRT5) antibodyKRT5 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Keratin 5 (KRT5) (AA 258-357) antibodyKRT5 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 2C8E4 unconjugated
anti-Keratin 5 (KRT5) (AA 331-430) antibodyKRT5 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 5 (KRT5) (AA 163-471) antibodyKRT5 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Keratin 5 (KRT5) (C-Term) antibodyKRT5 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. In Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))
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别名
- cytokeratin 5
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背景
- Keratin 5, also known as KRT5, K5, or CK5, dimerizes with keratin 14 and forms the intermediate filaments(IF) that make up the cytoskeleton of basal epithelial cells. This protein is involved in several diseases including epidermolysis bullosa simplex and breast and lung cancers. Keratin 5(and K14) are expressed primarily in basal keratinocytes in the epidermis, specifically in the stratified epithelium lining the skin and digestive tract. Keratin intermediate filaments make up the cytoskeletal scaffold within epithelial cells, which contributes to the cell architecture and provides the cells with the ability to withstand mechanical, and non-mechanical, stresses. K5/K14 keratin pairs are able to undergo extensive bundling due to the non-helical tail of K15 acting as a weak cross-linker at the intermediate filament surface. This bundling increase the elasticity, and therefore the mechanical resilience, of the intermediate filaments.
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UniProt
- P13647
抗原
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