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ING2 抗体 (AA 1-280)

This anti-ING2 antibody is a 小鼠 单克隆 antibody detecting ING2 in WB 和 EIA. Suitable for 人.
产品编号 ABIN5540825
发货至: 中国

Quick Overview for ING2 抗体 (AA 1-280) (ABIN5540825)

抗原

See all ING2 抗体
ING2 (Inhibitor of Growth Family, Member 2 (ING2))

适用

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宿主

  • 24
  • 5
  • 1
小鼠

克隆类型

  • 26
  • 4
单克隆

标记

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This ING2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)

克隆位点

AT39E5
  • 抗原表位

    • 7
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    AA 1-280

    纯化方法

    Protein-A affinity chromatography

    免疫原

    Recombinant human ING2 (1-280aa) purified from E. coli
  • 应用备注

    The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    ING2 (Inhibitor of Growth Family, Member 2 (ING2))

    别名

    ing2,ing1l

    背景

    ING2 is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis. This protein seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Also, It is component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides.

    UniProt

    Q9H160

    途径

    Chromatin Binding, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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