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CDK4 抗体 (AA 1-303)

The 小鼠 单克隆 anti-CDK4 antibody (Clone AT6D10) (ABIN5540806) specifically detects CDK4 in WB 和 EIA. The antibody is reactive with 人 samples.
产品编号 ABIN5540806
发货至: 中国
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Quick Overview for CDK4 抗体 (AA 1-303) (ABIN5540806)

抗原

See all CDK4 抗体
CDK4 (Cyclin-Dependent Kinase 4 (CDK4))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CDK4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)

克隆位点

AT6D10
  • 抗原表位

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    AA 1-303

    纯化方法

    Protein-A affinity chromatography

    免疫原

    Recombinant human CDK4 (1-303aa) purified from E. coli

    亚型

    IgG2a
  • 应用备注

    The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.Recommended starting dilution is 1:500.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    CDK4 (Cyclin-Dependent Kinase 4 (CDK4))

    别名

    cdk4

    背景

    Cyclin-dependent kinase 4, also known as CDK4, belongs to the cyclin-dependent kinases (CDK) family. CDKs are a family of protein kinases first discovered for their role in regulating the cell cycle. They are also involved in regulating transcription, mRNA processing, and the differentiation of nerve cells. CDK4, in complex with D-type cyclins, is thought to regulate cell growth during the G1 phase of the cell cycle. This association with a D-type cyclin up-regulates CDK4 activity, whereas binding to the CDK inhibitor p16 down-regulates CDK4 activity.

    UniProt

    P11802

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases, Regulation of Cell Size
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