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VEGFC 抗体 (AA 101-221) (Biotin)

This anti-VEGFC antibody is a 兔 多克隆 antibody detecting VEGFC in EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5540710
发货至: 中国
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Quick Overview for VEGFC 抗体 (AA 101-221) (Biotin) (ABIN5540710)

抗原

See all VEGFC 抗体
VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This VEGFC antibody is conjugated to Biotin

应用范围

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Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 101-221

    特异性

    The unconjugated antibody will react with Rat VEGF-C and will cross-react with Human and Mouse VEGF-C proteins.

    纯化方法

    Affinity Chromatography on Protein A

    免疫原

    Recombinant Rat VEGF-C native protein (Asp101-Ile221) derived from insect cells (Cat.-No DA3519X)

    亚型

    IgG
  • 应用备注

    ELISA: 1-5 μg/mL.

    限制

    仅限研究用
  • 储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

    别名

    vegf-c,flt4-l

    背景

    VEGF-C, a member of the VEGF/PDGF family of structurally related proteins, is a potent angiogenic cytokine. It promotes endothelial cell growth, promotes lymphangiogesis, and can also affect vascular permeability. VEGF-C is expressed in various tissues, but is not produced in peripheral blood lymphocytes. It forms cell surfaced-associated non-covalent disulfide linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. During embryogenesis, VEGF-C may play a role in the formation of the venous and lymphatic vascular systems. Both VEGF-C and VEGF-D are over-expressed in certain cancers, and the resulting elevated levels of VEGF-C or VEGF-D tend to correlate with increased lymphatic metastasis. Recombinant, fully processed rat VEGF-C is a 16-18 kDa non-disulfide linked homodimeric protein consisting of two 116 amino acid polypeptide chains. Due to glycosylation the protein migrates as a 20.0-22.0 kDa band under non-reducing condition.

    UniProt

    O35757

    途径

    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2
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