IL9 Receptor 抗体
Our Local Distributor
北京 101111
Quick Overview for IL9 Receptor 抗体 (ABIN5540440)
抗原
See all IL9 Receptor (IL9R) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- This antibody recognizes CD129 / IL-9R alpha, a 57 kDa type I transmembrane glycoprotein expressed at low levels by lymphocytes, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons.
-
纯化方法
- Protein-A affinity chromatography (> 95% pure by SDS-PAGE)
-
免疫原
- Human CD129-transfected cell line
-
亚型
- IgG2b
-
-
-
-
应用备注
- Flow cytometry: Use bright fluorochromes or signal multiplying detection. ELISA. Functional application: blocking.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- 95 % pure by SDS-PAGE) Buffer System: Phosphate buffered saline (PBS) Preservatives: 15 mM sodium azide, approx. pH 7.4
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
-
有效期
- 12 months
-
-
- IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))
-
别名
- cd129,il9r
-
背景
- CD129 serves as the high affinity alpha subunit of IL-9 receptor. It associates with CD132, the common gamma chain shared by receptors of many different cytokines. CD129 is expressed at low levels by T and B cells, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. Its signaling (through JAK/STAT pathways) results in proliferative and anti-apoptotic response, which is critical e.g. for intrathymic T cell development and survival of various cell types. The gene for CD129 is located at the pseudoautosomal regions of X and Y chromosomes and it may be related with the development of asthma.
-
UniProt
- Q01113
-
途径
- JAK/STAT Signaling, Growth Factor Binding
抗原
-