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IL9 Receptor 抗体

This anti-IL9 Receptor antibody is a 小鼠 单克隆 antibody detecting IL9 Receptor in FACS, Func 和 EIA. Suitable for 人.
产品编号 ABIN5540440
发货至: 中国

Quick Overview for IL9 Receptor 抗体 (ABIN5540440)

抗原

See all IL9 Receptor (IL9R) 抗体
IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))

适用

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宿主

  • 33
  • 12
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小鼠

克隆类型

  • 31
  • 15
  • 1
单克隆

标记

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This IL9 Receptor antibody is un-conjugated

应用范围

  • 26
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Flow Cytometry (FACS), Functional Studies (Func), Enzyme Immunoassay (EIA)

克隆位点

AH9R7
  • 特异性

    This antibody recognizes CD129 / IL-9R alpha, a 57 kDa type I transmembrane glycoprotein expressed at low levels by lymphocytes, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons.

    纯化方法

    Protein-A affinity chromatography (> 95% pure by SDS-PAGE)

    免疫原

    Human CD129-transfected cell line

    亚型

    IgG2b
  • 应用备注

    Flow cytometry: Use bright fluorochromes or signal multiplying detection. ELISA. Functional application: blocking.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    95 % pure by SDS-PAGE) Buffer System: Phosphate buffered saline (PBS) Preservatives: 15 mM sodium azide, approx. pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))

    别名

    cd129,il9r

    背景

    CD129 serves as the high affinity alpha subunit of IL-9 receptor. It associates with CD132, the common gamma chain shared by receptors of many different cytokines. CD129 is expressed at low levels by T and B cells, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. Its signaling (through JAK/STAT pathways) results in proliferative and anti-apoptotic response, which is critical e.g. for intrathymic T cell development and survival of various cell types. The gene for CD129 is located at the pseudoautosomal regions of X and Y chromosomes and it may be related with the development of asthma.

    UniProt

    Q01113

    途径

    JAK/STAT Signaling, Growth Factor Binding
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