IL9 Receptor 抗体 (pSer519)
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北京 101111
Quick Overview for IL9 Receptor 抗体 (pSer519) (ABIN1531670)
抗原
See all IL9 Receptor (IL9R) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 472-521, pSer519
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原理
- IL-9R (phospho Ser519) Antibody
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特异性
- Phospho-IL-9R (S519) Polyclonal Antibody detects endogenous levels of IL-9R protein only when phosphorylated at S519.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human IL-9R around the phosphorylation site of Ser519. AA range:472-521
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))
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别名
- IL-9R
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背景
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Synonyms: IL9R, Interleukin-9 receptor, IL-9 receptor, IL-9R, CD antigen CD129
Background: The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008],
Gene Name: IL9R
Protein Name: Interleukin-9 receptor
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分子量
- 57 kDa
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基因ID
- 3581
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OMIM
- 300007
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UniProt
- Q01113
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途径
- JAK/STAT Signaling, Growth Factor Binding
抗原
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