GDF15 抗体 (N-Term)
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北京 101111
Quick Overview for GDF15 抗体 (N-Term) (ABIN5540380)
抗原
See all GDF15 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 30-194, N-Term
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特异性
- Recognizes Human Macrophage Inhibitory Cytokine-1 (MIC-1). Other species not tested.
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纯化方法
- Affinity Chromatography on Protein G
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免疫原
- Genetic immunisation with cDNA encoding amino acids 30-194 (N-term) of MIC-1 proprotein.
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亚型
- IgG1
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anti-Growth Differentiation Factor 15 (GDF15) (AA 49-308) antibody
GDF15 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (C-Term) antibodyVerified GDF15 适用: 人 WB, ELISA, IHC, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 51-79) antibodyGDF15 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 221-308) antibodyGDF15 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 30-308) antibodyGDF15 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (C-Term) antibody (Biotin)GDF15 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal Biotin
anti-Growth Differentiation Factor 15 (GDF15) (AA 195-308) antibodyGDF15 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 16-143) antibodyGDF15 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 198-308) antibodyGDF15 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (N-Term) antibodyGDF15 适用: 人 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400. Flow Cytometry: 1.2 μg/10 6 cells.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Phosphate buffered saline, pH 7.2 without preservatives
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- GDF15 (Growth Differentiation Factor 15 (GDF15))
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别名
- gdf15
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背景
- Macrophage inhibitory cytokine-1 (MIC-1) is a member of the transforming growth factor-ß superfamily that regulates a wide variety of physiological processes involved in tissue differentiation and maintenance (1). MIC-1 is synthesized as a 62- kDa intracellular protein, which, after cleavage by a furin like protease, is secreted as a 25- kDa disulphide-linked dimeric protein. Expression of MIC-1 results in inhibition of macrophage activation, regulated by the p53 pathway, in response to pro-inflammatory monokines (1,2). MIC-1 is involved in tumour pathogenesis and its measurement can be used as a clinical tool for the diagnosis of a wide range of cancers. It could be a useful marker for aggressive prostate cancer while MIC-1 is upregulated in advanced and more aggressive prostatic tumours (3).
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UniProt
- Q99988
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途径
- SARS-CoV-2 Protein Interactome
抗原
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