NGFR 抗体 (AA 1-160) (Biotin)
Quick Overview for NGFR 抗体 (AA 1-160) (Biotin) (ABIN5540156)
抗原
See all NGFR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-160
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特异性
- This antibody recognizes CD271/NGFR, a 75 kDa transmembrane glycoprotein of the TNFR superfamily. The epitope is localized within ammino acids 1 - 160.
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免疫原
- Purified CD271 protein isolated from human melanoma cell line A875
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亚型
- IgG1
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应用备注
- Indirect immunofluorescence analysis by Flow cytometry: 1:200 as starting point.
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限制
- 仅限研究用
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状态
- Liquid
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
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有效期
- 12 months
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- NGFR (Nerve Growth Factor Receptor (NGFR))
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别名
- cd271,ngfr
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背景
- CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.
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UniProt
- P08138
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途径
- NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
抗原
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