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WWOX 抗体 (C-Term)

This anti-WWOX antibody is a 兔 多克隆 antibody detecting WWOX in WB. Suitable for 小鼠.
产品编号 ABIN5537702
发货至: 中国

Quick Overview for WWOX 抗体 (C-Term) (ABIN5537702)

抗原

See all WWOX 抗体
WWOX (WW Domain Containing Oxidoreductase (WWOX))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This WWOX antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 369-396, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This WWOX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 369-396 amino acids from the C-terminal region of human WWOX.

    亚型

    Ig Fraction
  • 应用备注

    For WB starting dilution is: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    WWOX (WW Domain Containing Oxidoreductase (WWOX))

    别名

    WWOX

    背景

    WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD). The highest normal expression of this gene is detected in hormonally regulated tissues such as testis, ovary, and prostate. This expression pattern and the presence of an SRD domain suggest a role for this gene in steroid metabolism. The encoded protein is more than 90 % identical to the mouse protein, which is an essential mediator of tumor necrosis factor-alpha-induced apoptosis, suggesting a similar, important role in apoptosis for the human protein. In addition, there is evidence that this gene behaves as a suppressor of tumor growth. Alternative splicing of this gene generates transcript variants that encode different isoforms.

    分子量

    47 kDa

    基因ID

    51741

    UniProt

    Q9NZC7
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