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USP4 抗体 (C-Term)

USP4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5537687
发货至: 中国
  • 抗原 See all USP4 抗体
    USP4 (Ubiquitin Specific Peptidase 4 (USP4))
    抗原表位
    • 15
    • 10
    • 10
    • 8
    • 8
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 903-933, C-Term
    适用
    • 51
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 50
    • 1
    • 1
    克隆类型
    • 51
    • 1
    多克隆
    标记
    • 25
    • 6
    • 6
    • 6
    • 4
    • 4
    • 1
    This USP4 antibody is un-conjugated
    应用范围
    • 37
    • 34
    • 31
    • 8
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    免疫原
    This USP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 903-933 amino acids from the C-terminal region of human USP4.
    亚型
    Ig Fraction
    Top Product
    Discover our top product USP4 Primary Antibody
  • 应用备注
    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    2 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    USP4 (Ubiquitin Specific Peptidase 4 (USP4))
    别名
    USP4 (USP4 产品)
    别名
    UNP antibody, Unph antibody, F730026I20Rik antibody, Unp antibody, mKIAA4155 antibody, ubiquitin specific peptidase 4 antibody, ubiquitin specific peptidase 4 (proto-oncogene) antibody, USP4 antibody, Usp4 antibody
    背景
    Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.
    分子量
    109 kDa
    基因ID
    7375
    UniProt
    Q13107
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