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USP4 抗体 (C-Term)

This anti-USP4 antibody is a 兔 多克隆 antibody detecting USP4 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN5537687
发货至: 中国

Quick Overview for USP4 抗体 (C-Term) (ABIN5537687)

抗原

See all USP4 抗体
USP4 (Ubiquitin Specific Peptidase 4 (USP4))

适用

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宿主

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克隆类型

  • 45
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多克隆

标记

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This USP4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 903-933, C-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

    免疫原

    This USP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 903-933 amino acids from the C-terminal region of human USP4.

    亚型

    Ig Fraction
  • 应用备注

    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    2 mg/mL

    缓冲液

    Supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    USP4 (Ubiquitin Specific Peptidase 4 (USP4))

    别名

    USP4

    背景

    Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.

    分子量

    109 kDa

    基因ID

    7375

    UniProt

    Q13107
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