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- 抗原 See all ELANE 抗体
- ELANE (Elastase, Neutrophil Expressed (ELANE))
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抗原表位
- AA 13-39, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ELANE antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This Neutrophil elastase antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-39 amino acids from the N-terminal region of human Neutrophil elastase.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product ELANE Primary Antibody
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anti-Elastase, Neutrophil Expressed (ELANE) (AA 30-267) antibody
ELANE 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) (AA 140-267) antibodyELANE 适用: 人, 猴 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 6B6B10 unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) (AA 30-247) antibodyELANE 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) (AA 140-267) antibodyELANE 适用: 人, 大鼠 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 6B6G6 unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) (AA 101-200) antibodyELANE 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) antibodyELANE 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) (AA 30-267) antibodyELANE 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) antibodyELANE 适用: 人 ELISA, IHC, FACS 宿主: 兔 Monoclonal 2H12 unconjugated Recombinant Antibody
anti-Elastase, Neutrophil Expressed (ELANE) antibodyELANE 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) (AA 168-267) antibodyELANE 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4E11 unconjugated
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- 应用备注
- For WB starting dilution is: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.26 mg/mL
- 缓冲液
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- ELANE (Elastase, Neutrophil Expressed (ELANE))
- 别名
- Neutrophil elastase (ELANE 产品)
- 别名
- ELA2 antibody, GE antibody, HLE antibody, HNE antibody, NE antibody, PMN-E antibody, SCN1 antibody, Ela2 antibody, F430011M15Rik antibody, ela2 antibody, ELANE antibody, elastase, neutrophil expressed antibody, proteinase 3 antibody, ELANE antibody, Elane antibody, prtn3 antibody
- 背景
- Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins. The product of this gene hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix following the protein's release from activated neutrophils. The enzyme may play a role in degenerative and inflammatory diseases by its proteolysis of collagen-IV and elastin of the extracellular matrix. This protein degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is clustered with other serine protease gene family members, azurocidin 1 and proteinase 3 genes, at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation.
- 分子量
- 29 kDa
- 基因ID
- 1991
- UniProt
- P08246
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