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DKK4 抗体 (C-Term)

Name: DKK4 抗体 (C-Term)
SKU: ABIN5536032
Availability: OutOfStock

This anti-DKK4 antibody is a 兔多克隆 antibody detecting DKK4 in WB 和 IHC (p). Suitable for 人.

Antibody is used in Western blot to detect DKK4 in A375 cell lysate. (DKK4 抗体 (C-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (DKK4 抗体 (C-Term))

IHC

2 images

产品编号 ABIN5536032

发货至: 中国

Quick Overview for DKK4 抗体 (C-Term) (ABIN5536032)

抗原

See all DKK4 抗体

DKK4 (Dickkopf Homolog 4 (Xenopus Laevis) (DKK4))

适用

人

宿主

兔

克隆类型

多克隆

标记

This DKK4 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Discover our top product DKK4 Primary Antibody

抗原表位
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AA 188-217, C-Term

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This DKK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-217 amino acids from the C-terminal region of human DKK4.

亚型

Ig Fraction
anti-Dickkopf Homolog 4 (Xenopus Laevis) (DKK4) (AA 19-224) antibody
DKK4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Dickkopf Homolog 4 (Xenopus Laevis) (DKK4) (AA 107-212) antibody
DKK4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Dickkopf Homolog 4 (Xenopus Laevis) (DKK4) (AA 19-224) antibody
DKK4 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Dickkopf Homolog 4 (Xenopus Laevis) (DKK4) (AA 7-36), (N-Term) antibody
DKK4 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

anti-Dickkopf Homolog 4 (Xenopus Laevis) (DKK4) (C-Term) antibody
Verified DKK4 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Dickkopf Homolog 4 (Xenopus Laevis) (DKK4) (AA 1-224) antibody
DKK4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Dickkopf Homolog 4 (Xenopus Laevis) (DKK4) (AA 1-224) antibody
DKK4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Dickkopf Homolog 4 (Xenopus Laevis) (DKK4) (AA 37-141) antibody
DKK4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Dickkopf Homolog 4 (Xenopus Laevis) (DKK4) antibody
DKK4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Dickkopf Homolog 4 (Xenopus Laevis) (DKK4) antibody
DKK4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

限制

仅限研究用
状态

Liquid

浓度

0.5 mg/mL

缓冲液

Supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
抗原

DKK4 (Dickkopf Homolog 4 (Xenopus Laevis) (DKK4))

别名

DKK4

背景

DKK4, like DKK1, DKK2, and DKK3, possesses an N-terminal signal peptide and 2 conserved cysteine-rich domains, which are separated by a linker region and contain 10 cysteine residues each. The second cysteine region has a putative lipid-binding function that may facilitate WNT/DKK interactions at the plasma membrane. The linker region contains 50 to 55 amino acids in DKK1, DKK2, and DKK4, whereas in DKK3 it contains only 12 amino acids. All DKKs have several potential sites for cleavage by furin-type proteases. Northern blot analysis detected no expression of DKK4, but RT-PCR analysis detected DKK4 expression in cerebellum, T-cell, esophagus, and lung cDNA libraries. DKK4 blocks Xenopus Wnt8, Wnt3a, and Wnt2b, but not Dsh or Fz8, induction of a secondary axis in frog embryos, indicating that DKKs antagonize WNT function upstream of WNT receptors.

分子量

25 kDa

基因ID

27121

UniProt

Q9UBT3

途径

WNT signaling