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- 抗原 See all P-Glycoprotein products
- P-Glycoprotein
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抗原表位
- AA 647-677
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This P-Glycoprotein antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
- 免疫原
- This P-Glycoprotein (ABCB1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 647-677 amino acids from the Central region of human P-Glycoprotein (ABCB1).
- 亚型
- Ig Fraction
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anti-P-Glycoprotein antibody
适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-P-Glycoprotein antibody适用: 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-P-Glycoprotein (AA 647-677) antibody适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-P-Glycoprotein antibody适用: 人, Hamster WB, IHC, FACS, ICC 宿主: 小鼠 Monoclonal JSB-1 unconjugated
anti-P-Glycoprotein antibody适用: 人, Hamster WB, IHC, FACS 宿主: 小鼠 Monoclonal JSB-1 unconjugated
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- 应用备注
- For WB starting dilution is: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 2 mg/mL
- 缓冲液
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- P-Glycoprotein
- Abstract
- P-Glycoprotein 产品
- 别名
- ABC20 antibody, CD243 antibody, CLCS antibody, GP170 antibody, MDR1 antibody, P-GP antibody, PGY1 antibody, Abcb1 antibody, Mdr1a antibody, ABCB1 antibody, ABCB4 antibody, CMDR1 antibody, xemdr antibody, ATP binding cassette subfamily B member 1 antibody, ATP binding cassette subfamily B member 1A antibody, ATP binding cassette subfamily B member 1 L homeolog antibody, ABCB1 antibody, Abcb1a antibody, abcb1.L antibody
- 背景
- The membrane-associated ABCB1 protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. ABCB1 is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.
- 分子量
- 141 kDa
- 基因ID
- 5243
- UniProt
- P08183
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