TLR1 抗体 (C-Term)
Quick Overview for TLR1 抗体 (C-Term) (ABIN5535021)
抗原
See all TLR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 764-795, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This Mouse TLR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 764-795 amino acids from the C-terminal region of mouse TLR1.
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亚型
- Ig Fraction
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anti-Toll-Like Receptor 1 (TLR1) (AA 30-290) antibody
TLR1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 1 (TLR1) (AA 101-200) antibodyTLR1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 1 (TLR1) (AA 114-339) antibodyTLR1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 8-3# unconjugated
anti-Toll-Like Receptor 1 (TLR1) (AA 350-404) antibodyTLR1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 1 (TLR1) (AA 25-580) antibodyTLR1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 1 (TLR1) antibody (PE-Cy7)TLR1 适用: 人, 小鼠, 大鼠, Cow, 犬 WB, FACS 宿主: 兔 Polyclonal PE-Cy7
anti-Toll-Like Receptor 1 (TLR1) (AA 25-134) antibodyTLR1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 1 (TLR1) (AA 321-420) antibodyTLR1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- TLR1 (Toll-Like Receptor 1 (TLR1))
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别名
- TLR1
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背景
- Higher animals establish host defense by orchestrating innate and adaptive immunity. This is mediated by professional antigen presenting cells, i.e. dendritic cells (DCs). DCs can incorporate pathogens, produce a variety of cytokines, maturate, and present pathogen-derived peptides to T cells, thereby inducing T cell activation and differentiation. These responses are triggered by microbial recognition through type I transmembrane proteins, Toll-like receptors (TLRs) on DCs. TLRs consist of ten members and each TLR is involved in recognizing a variety of microorganism-derived molecular structures. TLR ligands include cell wall components, proteins, nucleic acids, and synthetic chemical compounds, all of which can activate DCs as immune adjuvants. Each TLR can activate DCs in a similar, but distinct manner. For example, TLRs can be divided into subgroups according to their type I interferon (IFN) inducing ability. TLR2 cannot induce IFN-alpha or IFN-beta, but TLR4 can lead to IFN-beta production. Meanwhile, TLR3, TLR7, and TLR9 can induce both IFN-alpha and IFN-beta. Recent evidences suggest that cytoplamic adapters for TLRs are especially crucial for this functional heterogeneity.
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分子量
- 91 kDa
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基因ID
- 21897
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UniProt
- Q9EPQ1
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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