CROT 抗体 (C-Term)
Quick Overview for CROT 抗体 (C-Term) (ABIN5534058)
抗原
See all CROT 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 414-445, C-Term
-
纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
-
免疫原
- This COT (MAP3K8/MEKK8) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 414-445 amino acids from the C-terminal region of human COT (MAP3K8/MEKK8).
-
亚型
- Ig Fraction
-
-
anti-Carnitine O-Octanoyltransferase (CROT) (AA 2-99) antibody
CROT 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A6 unconjugated
anti-Carnitine O-Octanoyltransferase (CROT) (AA 1-87) antibodyCROT 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Carnitine O-Octanoyltransferase (CROT) (AA 178-199) antibodyVerified CROT 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Carnitine O-Octanoyltransferase (CROT) (C-Term) antibodyVerified CROT 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Carnitine O-Octanoyltransferase (CROT) antibodyCROT 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Carnitine O-Octanoyltransferase (CROT) (AA 2-99) antibodyCROT 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Carnitine O-Octanoyltransferase (CROT) (Internal Region) antibodyCROT 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Carnitine O-Octanoyltransferase (CROT) (AA 1-87) antibodyCROT 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Carnitine O-Octanoyltransferase (CROT) (AA 49-79), (N-Term) antibodyCROT 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB19235 unconjugated
anti-Carnitine O-Octanoyltransferase (CROT) (AA 256-305), (pThr290) antibodyCROT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1.4 mg/mL
-
缓冲液
- Supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
-
- CROT (Carnitine O-Octanoyltransferase (CROT))
-
别名
- COT
-
背景
- Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MEKK8 is able to activate NF-kappa-B 1 by stimulating proteasome-mediated proteolysis of NF-kappa-B 1/p105. The protein appears to play an important role in the cell cycle. This cytoplasmic protein is expressed in several normal tissues and human tumor-derived cell lines. The 58 kDa form is activated specifically during the S and G2/M phases of the cell cycle. The longer form undergoes phosphorylation on Ser residues mainly, and the shorter form on both Ser and Thr residues.
-
分子量
- 53 kDa
-
基因ID
- 1326
-
UniProt
- P41279
-
途径
- Monocarboxylic Acid Catabolic Process
抗原
-
