CROT 抗体 (pThr290)
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北京 101111
Quick Overview for CROT 抗体 (pThr290) (ABIN1531220)
抗原
See all CROT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 256-305, pThr290
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原理
- Cot (phospho Thr290) Antibody
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特异性
- Phospho-Cot (T290) Polyclonal Antibody detects endogenous levels of Cot protein only when phosphorylated at T290.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human COT around the phosphorylation site of Thr290. AA range:256-305
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亚型
- IgG
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anti-Carnitine O-Octanoyltransferase (CROT) (AA 2-99) antibody
CROT 适用: 人 WB 宿主: 小鼠 Monoclonal 1A6 unconjugated
anti-Carnitine O-Octanoyltransferase (CROT) (C-Term) antibodyVerified CROT 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Carnitine O-Octanoyltransferase (CROT) (AA 178-199) antibodyVerified CROT 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Carnitine O-Octanoyltransferase (CROT) (AA 49-79), (N-Term) antibodyCROT 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB19235 unconjugated
anti-Carnitine O-Octanoyltransferase (CROT) (AA 1-87) antibodyCROT 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Carnitine O-Octanoyltransferase (CROT) antibodyCROT 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Carnitine O-Octanoyltransferase (CROT) (AA 1-87) antibodyCROT 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Carnitine O-Octanoyltransferase (CROT) (Internal Region) antibodyCROT 适用: 人, 小鼠, 大鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Carnitine O-Octanoyltransferase (CROT) (AA 2-99) antibodyCROT 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Carnitine O-Octanoyltransferase (CROT) (AA 41-140) antibodyCROT 适用: 人 WB, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CROT (Carnitine O-Octanoyltransferase (CROT))
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别名
- COT
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背景
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Synonyms: MAP3K8, COT, ESTF, Mitogen-activated protein kinase kinase kinase 8, Cancer Osaka thyroid oncogene, Proto-oncogene c-Cot, Serine/threonine-protein kinase cot, Tumor progression locus 2, TPL-2
Background: This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011],
Gene Name: MAP3K8
Protein Name: Mitogen-activated protein kinase kinase kinase 8
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分子量
- 52 kDa
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基因ID
- 1326
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OMIM
- 191195
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UniProt
- P41279
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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