BPNT1 抗体 (C-Term)
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北京 101111
Quick Overview for BPNT1 抗体 (C-Term) (ABIN5533621)
抗原
See all BPNT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 277-305, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This BPNT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-305 amino acids from the C-terminal region of human BPNT1.
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亚型
- Ig Fraction
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应用备注
- For WB starting dilution is: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.35 mg/mL
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缓冲液
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))
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别名
- BPNT1
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背景
- BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92 % identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
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分子量
- 33 kDa
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基因ID
- 10380
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UniProt
- O95861
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途径
- Inositol Metabolic Process
抗原
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