MLL3 抗体 (N-Term)
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北京 101111
Quick Overview for MLL3 抗体 (N-Term) (ABIN5532940)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1142-1175, N-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This MLL3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1142-1175 amino acids from the N-terminal region of human MLL3.
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亚型
- Ig Fraction
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应用备注
- For IHC-P starting dilution is: 1:25
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- MLL3 (KMT2C) (Histone-lysine N-methyltransferase 2C (KMT2C))
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别名
- MLL3
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背景
- Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Central component of the MLL2/3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation. KMT2C/MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder.
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分子量
- 541 kDa
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基因ID
- 58508
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UniProt
- Q8NEZ4
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途径
- Warburg Effect
抗原
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