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VEGFB 抗体 (AA 110-139)

VEGFB 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5532353
发货至: 中国
  • 抗原 See all VEGFB 抗体
    VEGFB (Vascular Endothelial Growth Factor B (VEGFB))
    抗原表位
    • 16
    • 12
    • 10
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 110-139
    适用
    • 82
    • 21
    • 21
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    宿主
    • 75
    • 13
    • 1
    克隆类型
    • 79
    • 10
    多克隆
    标记
    • 46
    • 9
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This VEGFB antibody is un-conjugated
    应用范围
    • 77
    • 37
    • 35
    • 14
    • 8
    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    免疫原
    This VEGFB (VEGF2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 110-139 amino acids from the Central region of human VEGFB (VEGF2).
    亚型
    Ig Fraction
    Top Product
    Discover our top product VEGFB Primary Antibody
  • 应用备注
    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    2 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    VEGFB (Vascular Endothelial Growth Factor B (VEGFB))
    别名
    VEGFB (VEGFB 产品)
    别名
    VEGFL antibody, VRF antibody, VEGF-B antibody, Vrf antibody, vascular endothelial growth factor B antibody, VEGFB antibody, Vegfb antibody
    背景
    Vascular endothelial growth factors (VEGFs) are a family of closely related growth factors having a conserved pattern of eight cysteine residues and sharing common VEGF receptors. VEGFs stimulate endothelial cells, induce angiogenesis, promote cell migration, increase vascular permeability, and inhibit apoptosis. VEGFB has structural similarities to VEGF and PIGF and is frequently co-expressed with VEGF. There are two alternatively spliced isoforms of VEGFB: VEGFB 167 and VEGFB 186. VEGFB 167, a highly basic heparin-binding protein, remains with the cell or extracellular matrix whereas, VEGFB 186 is readily secreted. VEGFB stimulates endothelial cell proliferation. VEGFB binds to the tyrosine kinase receptor VEGFR1 (flt1) and does not bind to VEGFR2. Vascular Endothelial Growth Factor B is widely expressed but is most abundant in heart, skeletal muscle, and pancreas. It has been suggested that VEGFB expression in human primary breast cancers is associated with lymph node metastasis. The genes that encode VEGFB have been mapped to chromosome 11q13.
    分子量
    22 kDa
    基因ID
    7423
    UniProt
    P49765
    途径
    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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