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SPHK2 抗体 (C-Term)

Name: SPHK2 抗体 (C-Term)
SKU: ABIN5532144
Availability: OutOfStock

This anti-SPHK2 antibody is a 兔多克隆 antibody detecting SPHK2 in WB 和 IHC (p). Suitable for 人.

Western blot analysis in HepG2 cell line lysates (35ug/lane). (SPHK2 抗体 (C-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. (SPHK2 抗体 (C-Term))

IHC

2 images

产品编号 ABIN5532144

发货至: 中国

Quick Overview for SPHK2 抗体 (C-Term) (ABIN5532144)

抗原

See all SPHK2 抗体

SPHK2 (Sphingosine Kinase 2 (SPHK2))

适用

人

宿主

兔

克隆类型

多克隆

标记

This SPHK2 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Discover our top product SPHK2 Primary Antibody

抗原表位
10

8

6

4

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 590-620, C-Term

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

免疫原

This SPHK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 590-620 amino acids from the C-terminal region of human SPHK2.

亚型

Ig Fraction
anti-Sphingosine Kinase 2 (SPHK2) (AA 590-620), (C-Term) antibody
SPHK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB03625 unconjugated

anti-Sphingosine Kinase 2 (SPHK2) (AA 1-654) antibody
SPHK2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Sphingosine Kinase 2 (SPHK2) (AA 101-200) antibody
SPHK2 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Sphingosine Kinase 2 (SPHK2) (N-Term) antibody
SPHK2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Sphingosine Kinase 2 (SPHK2) antibody
SPHK2 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Sphingosine Kinase 2 (SPHK2) (AA 1-654) antibody
SPHK2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Sphingosine Kinase 2 (SPHK2) (Tyr754) antibody
SPHK2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Sphingosine Kinase 2 (SPHK2) (AA 1-30), (N-Term) antibody
SPHK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB03623 unconjugated

anti-Sphingosine Kinase 2 (SPHK2) (AA 1-30) antibody
SPHK2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Sphingosine Kinase 2 (SPHK2) (AA 590-620) antibody
SPHK2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

限制

仅限研究用
状态

Liquid

浓度

2 mg/mL

缓冲液

Supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
抗原

SPHK2 (Sphingosine Kinase 2 (SPHK2))

别名

SPHK2

背景

Sphingosine Kinase (SphK) catalyzes the phosphorylation of the lipid sphingosine, creating the bioactive lipid sphingosine-1-phosphate (S1P). S1P subsequently signals through cell surface G protein-coupled receptors, as well as intracellularly, to modulate cell proliferation, survival, motility and differentiation. SphK is an important signaling enzyme which is activated by diverse agents, including growth factors that signal through receptor tyrosine kinases, agents activating G protein-coupled receptors, and immunoglobulin receptors. Two SphK isotypes, SphK-1 and SphK-2, have been cloned, and both isotypes are ubiquitously expressed. SphK-1 has been shown to mediate cell growth, prevention of apoptosis, and cellular transformation, and is upregulated in a variety of human tumors. In contrast, SphK-2 increases apoptosis, and may be responsible for phosphorylating and activating the immunosuppressive drug FTY720.

分子量

69 kDa

基因ID

56848

UniProt

Q9NRA0

途径

VEGF Signaling