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PPL 抗体 (C-Term)

This 兔 多克隆 anti-PPL antibody specifically detects PPL in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN5531915
发货至: 中国
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Quick Overview for PPL 抗体 (C-Term) (ABIN5531915)

抗原

See all PPL 抗体
PPL (Periplakin (PPL))

适用

  • 31
  • 9
  • 7
  • 1

宿主

  • 31
  • 2

克隆类型

  • 33
多克隆

标记

  • 24
  • 3
  • 2
  • 2
  • 1
  • 1
This PPL antibody is un-conjugated

应用范围

  • 30
  • 20
  • 10
  • 6
  • 6
  • 5
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1301-1330, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This PPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1301-1330 amino acids from the C-terminal region of human PPL.

    亚型

    Ig Fraction
  • 应用备注

    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.45 mg/mL

    缓冲液

    Supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    PPL (Periplakin (PPL))

    别名

    PPL

    背景

    The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling. [provided by RefSeq].

    分子量

    205 kDa

    基因ID

    5493

    UniProt

    O60437
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