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c-MYC 抗体 (AA 40-69)

MYC 适用: 人 WB, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5531643
发货至: 中国
  • 抗原 See all c-MYC (MYC) 抗体
    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
    抗原表位
    • 59
    • 48
    • 44
    • 41
    • 24
    • 22
    • 17
    • 15
    • 15
    • 13
    • 10
    • 7
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    • 1
    • 1
    • 1
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    • 1
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    AA 40-69
    适用
    • 359
    • 162
    • 114
    • 15
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    • 13
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    宿主
    • 277
    • 100
    • 7
    • 5
    • 3
    • 1
    • 1
    克隆类型
    • 272
    • 121
    多克隆
    标记
    • 192
    • 31
    • 24
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    • 8
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    • 5
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    • 1
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    This c-MYC antibody is un-conjugated
    应用范围
    • 287
    • 140
    • 97
    • 82
    • 75
    • 57
    • 55
    • 28
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    • 24
    • 17
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    Western Blotting (WB), Flow Cytometry (FACS)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This MYC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-69 amino acids from human MYC.
    亚型
    Ig Fraction
    Top Product
    Discover our top product MYC Primary Antibody
  • 应用备注
    For WB starting dilution is: 1:1000

    For FACS starting dilution is: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.36 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
    别名
    Myc Proto-Oncogene protein (MYC 产品)
    背景
    MYC is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of the gene encoding MYC have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
    分子量
    49 kDa
    基因ID
    4609
    UniProt
    P01106
    途径
    p53 Pathway, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect
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