MLH1 抗体 (AA 452-480)
Our Local Distributor
北京 101111
Quick Overview for MLH1 抗体 (AA 452-480) (ABIN5531594)
抗原
See all MLH1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 452-480
-
纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
免疫原
- This MLH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 452-480 amino acids from the Central region of human MLH1.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
-
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.4 mg/mL
-
缓冲液
- Supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
-
- MLH1 (MutL Homolog 1 (MLH1))
-
别名
- MLH1
-
背景
- This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.
-
分子量
- 85 kDa
-
基因ID
- 4292
-
UniProt
- P40692
-
途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
-