Metabotropic Glutamate Receptor 6 抗体 (C-Term)
Quick Overview for Metabotropic Glutamate Receptor 6 抗体 (C-Term) (ABIN5531586)
抗原
See all Metabotropic Glutamate Receptor 6 (GRM6) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 832-861, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This Metabotropic Glutamate Receptor 6 (GPRC1F) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 832-861 amino acids from the C-terminal region of human Metabotropic Glutamate Receptor 6 (GPRC1F).
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亚型
- Ig Fraction
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应用备注
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For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))
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别名
- Metabotropic Glutamate Receptor 6
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背景
- L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
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分子量
- 95 kDa
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基因ID
- 2916
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UniProt
- O15303
抗原
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