电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

GREM1 抗体 (C-Term)

This anti-GREM1 antibody is a 兔 多克隆 antibody detecting GREM1 in WB 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN5531272
发货至: 中国

Quick Overview for GREM1 抗体 (C-Term) (ABIN5531272)

抗原

See all GREM1 抗体
GREM1 (Gremlin 1 (GREM1))

适用

  • 85
  • 48
  • 23
  • 7
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 90
  • 14
  • 1
  • 1

克隆类型

  • 91
  • 15
多克隆

标记

  • 52
  • 16
  • 12
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GREM1 antibody is un-conjugated

应用范围

  • 91
  • 47
  • 37
  • 21
  • 13
  • 13
  • 13
  • 7
  • 5
  • 3
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 15
    • 13
    • 10
    • 9
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 147-175, C-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

    免疫原

    This GREMLIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-175 amino acids from the C-terminal region of mouse GREMLIN.

    亚型

    Ig Fraction
  • 应用备注

    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    2 mg/mL

    缓冲液

    Supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    GREM1 (Gremlin 1 (GREM1))

    别名

    GREMLIN

    背景

    GREMLIN is a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth.

    分子量

    21 kDa

    基因ID

    23892

    UniProt

    O70326

    途径

    Regulation of Muscle Cell Differentiation, Tube Formation, Maintenance of Protein Location
You are here:
Chat with us!