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ARNT 抗体 (AA 513-544)

This anti-ARNT antibody is a 兔 多克隆 antibody detecting ARNT in WB 和 IF. Suitable for 人.
产品编号 ABIN5530297
发货至: 中国

Quick Overview for ARNT 抗体 (AA 513-544) (ABIN5530297)

抗原

See all ARNT 抗体
ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

适用

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宿主

  • 48
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克隆类型

  • 40
  • 31
多克隆

标记

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This ARNT antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

    • 6
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    AA 513-544

    纯化方法

    This antibody is purified through a protein G column, followed by dialysis against PBS.

    免疫原

    This ARNT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 513-544 amino acids from the Central region of human ARNT.

    亚型

    Ig Fraction
  • 应用备注

    For IF starting dilution is: 1:10~50

    For WB starting dilution is: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    2 mg/mL

    缓冲液

    Supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

    别名

    ARNT

    背景

    The aryl hydrocarbon (Ah) receptor is involved in the induction of several enzymes that participate in xenobiotic metabolism. The ligand-free, cytosolic form of the Ah receptor is complexed to heat shock protein 90. Binding of ligand, which includes dioxin and polycyclic aromatic hydrocarbons, results in translocation of the ligand-binding subunit only to the nucleus. Induction of enzymes involved in xenobiotic metabolism occurs through binding of the ligand-bound Ah receptor to xenobiotic responsive elements in the promoters of genes for these enzymes. This gene encodes a protein that forms a complex with the ligand-bound Ah receptor, and is required for receptor function. The encoded protein has also been identified as the beta subunit of a heterodimeric transcription factor, hypoxia-inducible factor 1. A t(1,12)(q21,p13) translocation, which results in a TEL-ARNT fusion protein, is associated with acute myeloblastic leukemia. Alternative splicing results in multiple transcript variants.

    分子量

    87 kDa

    基因ID

    405

    UniProt

    P27540

    途径

    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effect
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