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R-RAS2 抗体

适用: 人 ELISA, FACS, ICC, WB 宿主: 小鼠 Monoclonal EM-50 unconjugated
产品编号 ABIN5526909
发货至: 中国
  • 抗原
    R-RAS2
    适用
    宿主
    • 1
    小鼠
    克隆类型
    • 1
    单克隆
    标记
    • 1
    非结合性
    应用范围
    ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Western Blotting (WB)
    原理
    Anti-R-RAS2 Purified
    特异性
    The mouse monoclonal antibody EM-50 recognizes R-Ras2 / TC21 protein (intracellular antigen) and does not react with R-Ras1, H-Ras, K-Ras, and N-Ras.
    交叉反应 (详细)
    Human
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Human TC21
    克隆位点
    EM-50
    亚型
    IgG1 kappa
  • 应用备注
    Flow cytometry: Recommended dilution: 1-4 μg/mL. Intracellular staining.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • 抗原
    R-RAS2
    背景
    RAS related 2,R-Ras2 / TC21 is the only member of R-Ras family of small GTPases that shows transforming activities similar to H-Ras, N-Ras, and K-Ras, and it is also structurally similar to them. R-Ras2 seems to play an important role in activating signal transduction pathways that control cell proliferation. Its mutations are associated with the growth of certain tumors, but also overexpression of the wild type form of R-Ras2 has been frequently detected in various carcinomas. Pseudogenes of R-Ras2 gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants.,TC21, RRAS2
    基因ID
    22800
    UniProt
    P62070
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