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TREM1 抗体 (AA 21-202)

TREM1 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5519069
发货至: 中国
  • 抗原 See all TREM1 抗体
    TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))
    抗原表位
    • 16
    • 16
    • 8
    • 8
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-202
    适用
    • 63
    • 44
    • 34
    • 16
    • 4
    • 1
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 71
    • 17
    • 8
    克隆类型
    • 73
    • 22
    多克隆
    标记
    • 44
    • 7
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This TREM1 antibody is un-conjugated
    应用范围
    • 87
    • 49
    • 33
    • 26
    • 14
    • 13
    • 9
    • 9
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for TREM1 detection. Tested with WB, ELISA(Cap) in Mouse,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for TREM1 detection. Tested with WB, ELISA(Cap) in Mouse,Rat.
    Gene Name: triggering receptor expressed on myeloid cells 1
    Protein Name: Triggering receptor expressed on myeloid cells 1
    纯化方法
    Immunogen affinity purified.
    免疫原
    E. coli-derived mouse TREM1 recombinant protein (Position: A21-S202).
    亚型
    IgG
    Top Product
    Discover our top product TREM1 Primary Antibody
  • 应用备注
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Zhou, Xiong, Huang, Tang, Yu, Lan: "Identification of Genes Associated with Smad3-dependent Renal Injury by RNA-seq-based Transcriptome Analysis." in: Scientific reports, Vol. 5, pp. 17901, (2016) (PubMed).

  • 抗原
    TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))
    别名
    Trem1 (TREM1 产品)
    背景
    Trem1, Triggering receptor expressed on myeloid cells-1, is encoded by Trem1 gene. The expression of Trem1 is in monocytes and neutrophils but not in lymphocytes, dendritic cells, or other cell types. Trem1 is a 30-kD glycoprotein that is reduced to 26 kD by deglycosylation, in agreement with the predicted molecular mass. The Trem1 gene which contains 4 exons maps to chromosome 6p21.1, within a TREM gene cluster and the mouse Trem1 gene maps to chromosome 17 in a region that shows homology of synteny to human chromosome 6. The expression of Trem1 is upregulated by stimulation with lipopolysaccharide (LPS), gram-negative bacteria, and fungi. Cross-linking of Trem1 on neutrophils induces interleukin-8 (IL8) and myeloperoxidase secretion, while cross-linking on monocytes induces not only secretion of IL8 but also of monocyte chemotactic protein-1 (MCP1, or SCYA2) and tumor necrosis factor (TNF), MCP1 and TNF secretion could be further upregulated by LPS-mediated priming. Trem1 engagement also induces upregulation of adhesion molecules (e.g., ITGB1) and costimulatory molecules (e.g., CD40). Trem1 is associated with DAP12 (TYROBP), a molecule frequently associated with activating receptors.

    Synonyms: Triggering receptor expressed on myeloid cells 1, TREM-1, CD354, Trem1
    基因ID
    58217
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